Why Doesn't A Treatment For Neuropathy In The Legs And Feet Always Deliver Lasting Relief?
You've probably already tried prescription medications, creams, physical therapy, vitamin supplements — or a combination of several approaches.
Many conventional treatments were designed to help manage discomfort. But helping people cope with burning, tingling, or numbness isn't necessarily the same as addressing why those sensations keep returning.
That question led Dr. Ohsumi back to decades of scientific research.
The Discovery That Changed Everything
For more than 40 years, Dr. Yoshinori Ohsumi dedicated his career to understanding how cells repair and renew themselves.
His groundbreaking work in cell biology earned him the 2016 Nobel Prize in Physiology or Medicine.
Dr. Yoshinori Ohsumi — 2016 Nobel Prize in Physiology or Medicine
When his wife, Mariko, developed peripheral neuropathy, watching someone he loved continue to struggle despite trying multiple conventional treatments changed the direction of his research. Instead of accepting temporary relief as the only option, he returned to decades of scientific work to investigate what might actually be driving nerve damage.
His research suggests that the problem may not begin with the nerves themselves, but with the depletion of essential nutrients that help keep them healthy.
As these nutrients decline, an enzyme called MMP13 may become overactive, triggering the formation of what he describes as Sticky Plaque.
Over time, this buildup may begin to interfere with the protective layer that surrounds your nerves — known as the myelin sheath. As that protective coating becomes weaker, nerve signals may no longer travel the way they should, leading to burning, tingling, numbness, pain, and other symptoms associated with peripheral neuropathy.
The Nerve Reset Protocol
Those findings became the foundation of what Dr. Ohsumi now calls the Nerve Reset Protocol — a natural, Japanese-inspired approach designed to support the body's ability to protect and restore healthy nerve function rather than simply masking symptoms. In the free educational presentation, Dr. Ohsumi explains the entire process step by step.